CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24700
Family Name P2X purinoceptor 7 inhibitor 2-(2,3-dichlorophenyl)-N-[(2-methylsulfonylphenyl)methyl]-1,2,4-triazol-3-amine family
No. of Seeds 4 No. of Other Members 17
Family Centroid CFAMM00471146 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Cellular tumor antigen p53 Binder Superfamily
Class Class 5630

Cousin Family NamesSeedsMembers
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 3
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 1
Sigma non-opioid intracellular receptor 1 ligand 1-(3,4-dichlo... 2 19
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
P2X purinoceptor 7 inhibitor N-benzyl-1-(2,3-dichlorophenyl)te... 19 0
P2X purinoceptor 7 inhibitor 1-(2,3-dichlorophenyl)-N-[(2-morp... 1 0
P2X purinoceptor 7 inhibitor 4-(2,3-dichlorophenyl)-N-[(2-thio... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471154 CHEMBL403763 Bioactive 2-(2,3-dichlorophenyl)-N-[(2-methylsulfanylphenyl)methyl]-1,2,4-triazol-3-amine
CFAMM00471140 CHEMBL1778018 Bioactive 1-(2,3-dichlorophenyl)-N-[(2-methylsulfanylphenyl)methyl]tetrazol-5-amine
CFAMM00471153 CHEMBL1778008 Bioactive 1-(2,3-dichlorophenyl)-N-[(2-methylsulfonylphenyl)methyl]tetrazol-5-amine
CFAMM00471146 CHEMBL403222 Bioactive 2-(2,3-dichlorophenyl)-N-[(2-methylsulfonylphenyl)methyl]-1,2,4-triazol-3-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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