CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24702
Family Name P2X purinoceptor 7 inhibitor N-benzyl-1-(2,3-dichlorophenyl)tetrazol-5-amine family
No. of Seeds 19 No. of Other Members 0
Family Centroid CFAMM00471177 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 3065

Cousin Family NamesSeedsMembers
HCV NS4B protein Inhibitor Clemizole Family 2 43
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 3
Sigma non-opioid intracellular receptor 1 ligand 1-(3,4-dichlo... 2 19
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Pteridine reductase, putative inhibitor 1-[(3,4-dichlorophenyl... 2 1
P2X purinoceptor 7 inhibitor 2-(2,3-dichlorophenyl)-N-[(2-meth... 4 17
P2X purinoceptor 7 inhibitor 1-(2,3-dichlorophenyl)-N-[(2-morp... 1 0
P2X purinoceptor 7 inhibitor 4-(2,3-dichlorophenyl)-N-[(2-thio... 2 0


External ID

Functional Category

Molecule Name

CFAMM00471177 CHEMBL1778011 Bioactive N-benzyl-1-(2,3-dichlorophenyl)tetrazol-5-amine
CFAMM00471176 CHEMBL1778013 Bioactive 1-(2,3-dichlorophenyl)-N-(2-methylphenyl)tetrazol-5-amine
CFAMM00471175 CHEMBL1778012 Bioactive 1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]tetrazol-5-amine
CFAMM00471180 CHEMBL1778121 Bioactive 1-(2,3-dichlorophenyl)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]tetrazol-5-amine
CFAMM00471179 CHEMBL1778015 Bioactive 1-(2,3-dichlorophenyl)-N-[(3-fluorophenyl)methyl]tetrazol-5-amine
CFAMM00471178 CHEMBL1778014 Bioactive 1-(2,3-dichlorophenyl)-N-[(2-fluorophenyl)methyl]tetrazol-5-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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