CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24715
Family Name Protein kinase C alpha type inhibitor [(1R)-4-dodecoxy-1-(hydroxymethyl)-3-oxo-2-benzofuran-1-yl]methyl 2-tert-butyl-3,3-dimethylbutanoate family
No. of Seeds 1 No. of Other Members 18
Family Centroid CFAMM00471222 Functional Category Bioactive with Natural Product
Superfamily Estrogen receptor beta and Protein kinase C alpha type Binder Superfamily
Class Class 776

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Rotenone family 16 107
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Eukaryotic initiation factor 4A-I inhibitor methyl (1R,2R,3S,3... 12 1
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Survival motor neuron protein and Prelamin-A/C inhibitor CHEMB... 2 32
Prenol Lipids Metabolite Austalide A Family 5 4
Prenol Lipids Metabolite 13-Hydroxydihydromelleolide Family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471222 CHEMBL1778819 Bioactive [(1R)-4-dodecoxy-1-(hydroxymethyl)-3-oxo-2-benzofuran-1-yl]methyl 2-tert-butyl-3,3-dimethylbutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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