CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24733
Family Name Corticotropin-releasing factor receptor 1 ligand AGN-PC-02ZKZ9 family
No. of Seeds 9 No. of Other Members 12
Family Centroid CFAMM00471409 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Binder Superfamily 12
Class Class 96

Cousin Family NamesSeedsMembers
CC-486 family 7 103
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... 1 2
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... 2 10
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-02ZKS9... 2 0


External ID

Functional Category

Molecule Name

CFAMM00471411 CHEMBL433768 Bioactive AGN-PC-02ZKZB
CFAMM00471404 CHEMBL368041 Bioactive AGN-PC-02ZKSH
CFAMM00471410 CHEMBL181283 Bioactive AGN-PC-00E6MA
CFAMM00471403 CHEMBL369341 Bioactive AGN-PC-02ZKSK
CFAMM00471409 CHEMBL359832 Bioactive AGN-PC-02ZKZ9
CFAMM00471414 CHEMBL182482 Bioactive AGN-PC-02ZKRZ
CFAMM00471401 CHEMBL359956 Bioactive SureCN14446399
CFAMM00471413 CHEMBL178165 Bioactive AGN-PC-02ZKZH
CFAMM00471406 CHEMBL181227 Bioactive AGN-PC-02ZKZA

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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