CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2475
Family Name Coagulation factor X inhibitor 1-(6-chloronaphthalen-2-yl)sulfonyl-3-[2-(dimethylamino)ethyl]-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-3-methylurea family
No. of Seeds 12 No. of Other Members 13
Family Centroid CFAMM00334551 Functional Category Bioactive
Superfamily Coagulation factor X and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 3169

Cousin Family NamesSeedsMembers
Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[1-(ethyl... 27 1
C-C chemokine receptor type 5 ligand AGN-PC-075XPW family 3 3
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 6 1
Coagulation factor X inhibitor SureCN4463987 family 5 0
Cathepsin K inhibitor SureCN4163958 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334561 CHEMBL403106 Bioactive 6-chloro-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]naphthalene-1-sulfonamide
CFAMM00334554 CHEMBL1271160 Bioactive SureCN6362013
CFAMM00334560 CHEMBL256890 Bioactive 6-chloro-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-N-(3-hydroxypropyl)naphthalene-2-sulfonamide
CFAMM00334553 CHEMBL270255 Bioactive 1-(6-chloronaphthalen-2-yl)sulfonyl-3-[2-(dimethylamino)ethyl]-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]urea
CFAMM00334546 CHEMBL402828 Bioactive 1-(6-chloronaphthalen-2-yl)sulfonyl-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-3-methyl-3-(1-methylpiperidin-4-yl)urea
CFAMM00334552 CHEMBL408044 Bioactive methyl 2-[(6-chloronaphthalen-2-yl)sulfonyl-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]amino]acetate
CFAMM00334551 CHEMBL256628 Bioactive 1-(6-chloronaphthalen-2-yl)sulfonyl-3-[2-(dimethylamino)ethyl]-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-3-methylurea
CFAMM00334557 CHEMBL257854 Bioactive 1-(6-chloronaphthalen-2-yl)sulfonyl-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-3-(2-hydroxyethyl)-3-methylurea
CFAMM00334550 CHEMBL402031 Bioactive AGN-PC-04UAQI
CFAMM00334569 CHEMBL272136 Bioactive N-(6-chloronaphthalen-2-yl)sulfonyl-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-4-methylpiperazine-1-carboxamide
CFAMM00334549 CHEMBL270829 Bioactive 1-(6-chloronaphthalen-2-yl)sulfonyl-3-[2-(diethylamino)ethyl]-1-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]-3-methylurea
CFAMM00334568 CHEMBL271427 Bioactive 2-[(6-chloronaphthalen-2-yl)sulfonyl-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]amino]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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