CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24757
Family Name Tyrosine-protein kinase ABL1 inhibitor AGN-PC-04SU6B family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00471539 Functional Category Bioactive
Superfamily Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase ITK/TSK Binder Superfamily
Class Class 2633

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Arachidonate 5-lipoxygenase Inhibitor N-(thiazol-2-yl)benzamid... 3 53
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Tyrosine-protein kinase ABL1 inhibitor 5-[(5-{[4-{[4-(2-Hydrox... 4 1
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Neuropeptide Y receptor type 5 ligand 3-[[5-(2-methylbenzoyl)-... 2 8
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
High affinity nerve growth factor receptor and Hepatocyte grow... 6 8
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-03LEDF family 3 4
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-02WPOZ family 1 1


External ID

Functional Category

Molecule Name

CFAMM00471540 CHEMBL1784641 Bioactive AGN-PC-0A9TZO
CFAMM00471539 CHEMBL1784640 Bioactive AGN-PC-04SU6B

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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