CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2476
Family Name Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M770 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00329770 Functional Category Bioactive
Superfamily Aurora kinase B and Aurora kinase A Binder Superfamily
Class Class 3494

Cousin Family NamesSeedsMembers
PF-4217903 family 14 65
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M6EM fa... 11 88
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09QGL9 fa... 23 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M82N fa... 13 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M46L fa... 2 7
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 1
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Protein-tyrosine kinase 6 and Aurora kinase B inhibitor 1-[[5-... 1 0
Aurora kinase A and Aurora kinase B inhibitor N-[6-methyl-3-[1... 2 2
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 3
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 1 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Aurora kinase B and Aurora kinase A inhibitor N-(furan-2-ylmet... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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