CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2478
Family Name Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN3537186 family
No. of Seeds 5 No. of Other Members 56
Family Centroid CFAMM00334632 Functional Category Bioactive
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 4
Class Class 513

Cousin Family NamesSeedsMembers
Beta-secretase 1 and Beta-secretase 2 inhibitor 7-fluoro-3-(5-... 2 7
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 2 0
Beta-secretase 1 and Beta-secretase 2 inhibitor AGN-PC-076LAV ... 1 3


External ID

Functional Category

Molecule Name

CFAMM00334629 CHEMBL584926 Bioactive SureCN3535202
CFAMM00334605 CHEMBL584695 Bioactive SureCN3852693
CFAMM00334610 CHEMBL1271244 Bioactive (5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[3-(2-fluoropyridin-3-yl)phenyl]-3-methylimidazol-4-one
CFAMM00334599 CHEMBL2349506 Bioactive 2'-amino-2,2,3'-trimethyl-6-(5-prop-1-ynylpyridin-3-yl)spiro[3H-chromene-4,5'-imidazole]-4'-one
CFAMM00334632 CHEMBL567477 Bioactive SureCN3537186

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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