CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24786
Family Name Beta-secretase 1 inhibitor 3-[[[(2S)-2-[[(3S,4S)-3-hydroxy-6-methyl-4-[[(2S)-2-[[(2S,3S)-3-methyl-2-(oxane-2-carbonylamino)pentanoyl]amino]propanoyl]amino]heptanoyl]amino]-3-methylbutanoyl]amino]methyl]benzoic acid family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00471668 Functional Category Bioactive
Superfamily Plasmepsin-2 and Plasmepsin-1 Binder Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Atrial natriuretic peptide receptor 1 Ligand Nesiritide Family 6 111
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Thymopentin family 20 133
Thymosin Beta-4 family 8 30
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Beta-secretase 1 Inhibitor KMI-172 Family 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Disks large homolog 4 Inhibitor N-(3,4-difluorophenyl)propyl-e... 3 0
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Gamma-aminobutyric acid type B receptor subunit 1 ligand CGP-6... 3 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Pol polyprotein inhibitor AC1LADQG family 7 1
Pol polyprotein inhibitor AC1LA3AI family 5 9
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471668 CHEMBL1791017 Bioactive 3-[[[(2S)-2-[[(3S,4S)-3-hydroxy-6-methyl-4-[[(2S)-2-[[(2S,3S)-3-methyl-2-(oxane-2-carbonylamino)pentanoyl]amino]propanoyl]amino]heptanoyl]amino]-3-methylbutanoyl]amino]methyl]benzoic acid
CFAMM00471667 CHEMBL1791018 Bioactive 3-[[[(2S)-2-[[(3S,4S)-4-[[(2S)-2-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]hexanoyl]amino]methyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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