CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24817
Family Name Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-6-(1,3-oxazol-5-yl)-3-(2-pyridin-4-ylethyl)-2-sulfanylidene-1H-quinazolin-4-one family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00471905 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Inhibitor Tyverb/tykerb Superfamily
Class Class 678

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 140
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-2... 7 1
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN72661... 3 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor AC1LAY14 fa... 2 1


External ID

Functional Category

Molecule Name

CFAMM00471904 CHEMBL368056 Bioactive 7-methoxy-3-(2-morpholin-4-ylethyl)-6-(1,3-oxazol-5-yl)-2-sulfanylidene-1H-quinazolin-4-one
CFAMM00471903 CHEMBL414657 Bioactive 7-methoxy-6-(1,3-oxazol-5-yl)-3-(pyridin-4-ylmethyl)-2-sulfanylidene-1H-quinazolin-4-one
CFAMM00471902 CHEMBL180007 Bioactive 7-methoxy-3-methyl-6-(1,3-oxazol-5-yl)-2-sulfanylidene-1H-quinazolin-4-one
CFAMM00471901 CHEMBL197546 Bioactive 7-methoxy-3-methyl-6-(1,3-oxazol-5-yl)spiro[1H-quinazoline-2,5'-4,6-dihydrocyclopenta[b]thiophene]-4-one
CFAMM00471900 CHEMBL202190 Bioactive 1-O'-tert-butyl 2-O'-methyl (2S,2'R)-7-methoxy-3-methyl-6-(1,3-oxazol-5-yl)-4-oxospiro[1H-quinazoline-2,4'-pyrrolidine]-1',2'-dicarboxylate
CFAMM00471906 CHEMBL199075 Bioactive AGN-PC-075Y7U
CFAMM00471905 CHEMBL182139 Bioactive 7-methoxy-6-(1,3-oxazol-5-yl)-3-(2-pyridin-4-ylethyl)-2-sulfanylidene-1H-quinazolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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