CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24823
Family Name Protein-S-isoprenylcysteine O-methyltransferase inhibitor N-[2-(2,2-dimethyl-4-phenyloxan-4-yl)ethyl]-3,5-difluoro-4-methoxyaniline family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00472002 Functional Category Bioactive
Superfamily Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor Binder Superfamily 3
Class Class 1484

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Bip... 3 7
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
Substance-P receptor ligand 1-[(5-amino-2-methoxyphenyl)methyl... 3 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
Amyloid beta A4 protein inhibitor 2-(fluoranylmethyl)-3-[4-[(E... 1 3
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472002 CHEMBL1800496 Bioactive N-[2-(2,2-dimethyl-4-phenyloxan-4-yl)ethyl]-3,5-difluoro-4-methoxyaniline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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