CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24825
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2A ligand 3-[(E)-2-carboxy-2-(furan-3-yl)ethenyl]-4,6-dichloro-1H-indole-2-carboxylic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00472006 Functional Category Bioactive
Superfamily Thyroid hormone receptor beta and Thyroid hormone receptor alpha Binder Superfamily 8
Class Class 4064

Cousin Family NamesSeedsMembers
Sodium channel Ligand GSK1014802 Family 4 92
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family 5 14
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 1 1
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 7 5
Glutamate receptor ionotropic, NMDA 1 ligand AGN-PC-0ABXNN family 1 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 6 5


External ID

Functional Category

Molecule Name

CFAMM00472006 CHEMBL180067 Bioactive 3-[(E)-2-carboxy-2-(furan-3-yl)ethenyl]-4,6-dichloro-1H-indole-2-carboxylic acid
CFAMM00472005 CHEMBL361853 Bioactive 3-[(E)-2-carboxy-2-(furan-2-yl)ethenyl]-4,6-dichloro-1H-indole-2-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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