CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2483
Family Name Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00334663 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 2
Class Class 3216

Cousin Family NamesSeedsMembers
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Coagulation factor X and Trypsin-1 inhibitor 1-(3-carbamimidoy... 4 1
B1 bradykinin receptor ligand 2-[(2R)-7-chloro-1-naphthalen-2-... 2 0
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 12 3
Coagulation factor X and Prothrombin inhibitor 3-(6-chloronaph... 1 14
Coagulation factor X inhibitor 5-chloro-N-[1-[4-[2-[(dimethyla... 4 0
Coagulation factor X inhibitor [1-[4-[3-[(6-chloronaphthalen-2... 2 0
Coagulation factor X and Prothrombin inhibitor SureCN948339 fa... 5 14
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 2 0


External ID

Functional Category

Molecule Name

CFAMM00334663 CHEMBL1271369 Bioactive 6-chloro-N-[(3S)-1-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide
CFAMM00334662 CHEMBL272349 Bioactive 6-chloro-N-[1-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-2-oxopiperidin-3-yl]naphthalene-2-sulfonamide
CFAMM00334661 CHEMBL271659 Bioactive AGN-PC-076G7D
CFAMM00334672 CHEMBL402077 Bioactive 6-chloro-N-[1-(2-fluoro-4-imidazol-1-ylphenyl)-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide
CFAMM00334671 CHEMBL404218 Bioactive 6-chloro-N-[1-[2-fluoro-4-(1-methylimidazol-2-yl)phenyl]-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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