CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24836
Family Name Neuropeptide S receptor ligand 5-(4-chlorophenyl)-6-methoxy-5-(oxan-4-ylmethyl)imidazo[2,1-a]isoindole family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00472026 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear receptor subfamily 1 group I member 2 Binder Superfamily
Class Class 795

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Dual specificity protein kinase CLK1 and Dual specificity prot... 2 14
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Glucagon receptor ligand SureCN2647807 family 3 7
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
Beta-secretase 1 and Amyloid beta A4 protein inhibitor SureCN3... 1 5
Neuropeptide S receptor ligand 5-(4-bromophenyl)-5-(oxan-4-ylm... 1 5
Metabotropic glutamate receptor 5 ligand AGN-PC-0760YR family 1 0
C5a anaphylatoxin chemotactic receptor 1 ligand AGN-PC-077N2F ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472026 CHEMBL1801359 Bioactive 5-(4-chlorophenyl)-6-methoxy-5-(oxan-4-ylmethyl)imidazo[2,1-a]isoindole
CFAMM00472025 CHEMBL1801358 Bioactive 5-(4-chlorophenyl)-7-methoxy-5-(oxan-4-ylmethyl)imidazo[2,1-a]isoindole
CFAMM00472024 CHEMBL1801360 Bioactive 3-[5-(4-chlorophenyl)-7-methoxyimidazo[1,2-b]isoindol-5-yl]-1-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]propan-1-one
CFAMM00472023 CHEMBL1801361 Bioactive 3-[5-(4-chlorophenyl)-6-methoxyimidazo[1,2-b]isoindol-5-yl]-N,N-diethylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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