CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24837
Family Name P2X purinoceptor 7 inhibitor N-[(3-chloro-2-methylphenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00472030 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 Binder Superfamily
Class Class 1016

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Histamine H1 receptor Ligand Mizolastine Family 14 603
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Histone deacetylase 1 and Histone deacetylase 8 inhibitor (E)-... 3 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Cell division cycle 7-related protein kinase and Dual specific... 3 1
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 3 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Substance-P receptor ligand SureCN7659714 family 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472029 CHEMBL1801367 Bioactive N-[(3-chloro-2-methylphenyl)methyl]-2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)acetamide
CFAMM00472028 CHEMBL1801368 Bioactive N-[(2-chloro-6-methylphenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide
CFAMM00472027 CHEMBL1801369 Bioactive N-[(2-chloro-6-methylphenyl)methyl]-2-(3-ethyl-5-methyl-2-phenylimidazol-4-yl)acetamide
CFAMM00472033 CHEMBL1801455 Bioactive N-[(3-chloro-2-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3,5-dimethylimidazol-4-yl]acetamide
CFAMM00472032 CHEMBL1801456 Bioactive N-[(3-chloro-2-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]acetamide
CFAMM00472031 CHEMBL1801457 Bioactive N-[(2-chloro-6-methylphenyl)methyl]-2-[2-(2,4-difluorophenyl)-3-ethyl-5-methylimidazol-4-yl]acetamide
CFAMM00472030 CHEMBL1801366 Bioactive N-[(3-chloro-2-methylphenyl)methyl]-2-(3,5-dimethyl-2-phenylimidazol-4-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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