CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24853
Family Name DNA polymerase III PolC-type and DNA polymerase III subunit alpha inhibitor SureCN6324171 family
No. of Seeds 11 No. of Other Members 10
Family Centroid CFAMM00472103 Functional Category Bioactive
Superfamily Caspase-1 and Caspase-8 Binder Superfamily
Class Class 1306

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 16
Adenosine receptor A3 ligand (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlor... 5 1
Adenosine receptor A3 ligand (2R,3R,4S)-2-[2-chloro-6-[(3-fluo... 6 7
Adenosine receptor A1 ligand 3-chloro-N-[(2S,3R,4R,5R)-5-[6-(c... 1 0
78 kDa glucose-regulated protein and Heat shock cognate 71 kDa... 1 0


External ID

Functional Category

Molecule Name

CFAMM00472105 CHEMBL361838 Bioactive SureCN5774925
CFAMM00472091 CHEMBL182056 Bioactive SureCN5777710
CFAMM00472104 CHEMBL182401 Bioactive SureCN5777679
CFAMM00472097 CHEMBL180999 Bioactive SureCN1443265
CFAMM00472103 CHEMBL181909 Bioactive SureCN6324171
CFAMM00472090 CHEMBL183503 Bioactive 2-[(3,4-dichlorophenyl)methylamino]-7-(5-methylsulfinylpentyl)-3H-purin-6-one
CFAMM00472089 CHEMBL361426 Bioactive SureCN12173575
CFAMM00472108 CHEMBL369308 Bioactive [(2R)-6-[2-[(3,4-dichlorophenyl)methylamino]-6-oxo-3H-purin-7-yl]hexan-2-yl] acetate
CFAMM00472107 CHEMBL183856 Bioactive 2-[(3,4-dichlorophenyl)methylamino]-7-[(5R)-5-hydroxyhexyl]-3H-purin-6-one
CFAMM00472093 CHEMBL183459 Bioactive SureCN5799623
CFAMM00472106 CHEMBL180494 Bioactive SureCN5797123

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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