CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24866
Family Name Smoothened homolog inhibitor N-(2,6-dichloro-4-cyanophenyl)-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazine-7-carboxamide family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00472143 Functional Category Bioactive
Superfamily Integrin beta-2 and Androgen receptor Binder Superfamily
Class Class 3044

Cousin Family NamesSeedsMembers
Phospholipase D1 Inhibitor Halopemide Family 17 111
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
Smoothened homolog inhibitor N-(2,6-dichloro-4-methylsulfonylp... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472143 CHEMBL1808457 Bioactive N-(2,6-dichloro-4-cyanophenyl)-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazine-7-carboxamide
CFAMM00472139 CHEMBL1808458 Bioactive N-(2-chloro-4-cyano-6-methylphenyl)-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazine-7-carboxamide
CFAMM00472145 CHEMBL1813103 Bioactive (8aS)-N-[2,6-dichloro-4-(dimethylcarbamoyl)phenyl]-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazine-7-carboxamide
CFAMM00472144 CHEMBL1813102 Bioactive (8aS)-N-(2,6-dichloro-4-cyanophenyl)-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazine-7-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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