CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2487
Family Name Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-6-[(4-fluoro-3-methylphenyl)sulfonylamino]-N-hydroxyhexanamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00334681 Functional Category Bioactive
Superfamily Lethal factor Binder Superfamily
Class Class 3354

Cousin Family NamesSeedsMembers
Pan-DAC Inhibitor AR-42 Family 21 153
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334685 CHEMBL298635 Bioactive (2R)-2-(1,1-dioxo-7-phenyl-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl)-N-hydroxypropanamide
CFAMM00334681 CHEMBL1271419 Bioactive (2R)-2-(4-fluoro-3,5-dimethylanilino)-6-[(4-fluoro-3-methylphenyl)sulfonylamino]-N-hydroxyhexanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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