CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2488
Family Name Thymidylate synthase inhibitor AC1LAB7Z family
No. of Seeds 8 No. of Other Members 3
Family Centroid CFAMM00334689 Functional Category Bioactive
Superfamily Thymidylate synthase Binder Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
Thymidylate synthase inhibitor (2S)-2-[[4-[(2-methyl-4-oxo-1,6... 15 107
Thymidylate synthase inhibitor AC1LABAB family 14 3
Thymidylate synthase inhibitor (2R)-2-[[(4S)-4-carboxy-4-[[4-[... 55 43
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 11
Thymidylate synthase inhibitor AC1LAB82 family 17 0
Dihydrofolate reductase and Thymidylate synthase inhibitor 2-[... 10 5
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Thymidylate synthase inhibitor (2S)-2-[[(4S)-4-carboxy-4-[[(4S... 7 11
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 4 1
Folylpolyglutamate synthase, mitochondrial and Dihydrofolate r... 3 0
Dihydrofolate reductase inhibitor 2-[[4-[2-(2-amino-4-oxo-1,5,... 2 0
Thymidylate synthase inhibitor SureCN6446340 family 2 1
Cationic trypsin and Prothrombin inhibitor 2-ketobenzothiazole... 1 3
Trifunctional purine biosynthetic protein adenosine-3 inhibito... 1 0
Beta-secretase 1 inhibitor 3-[[(2R,3S)-3-[[(2S)-2-[[(2S)-2-[[(... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334688 CHEMBL127142 Bioactive AC1LAB7T
CFAMM00334687 CHEMBL348765 Bioactive 2-[[4-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]-3-(3-nitrophenyl)propanoic acid
CFAMM00334693 CHEMBL130518 Bioactive 5-amino-2-[[4-[[2-amino-4-oxo-5-(trifluoromethyl)-1H-quinazolin-6-yl]methylamino]benzoyl]amino]pentanoic acid
CFAMM00334686 CHEMBL439975 Bioactive AC1LAB7W
CFAMM00334691 CHEMBL6436 Bioactive (2R)-2-[[4-[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]-3,3-dimethylbutanoic acid
CFAMM00334690 CHEMBL6715 Bioactive (2R)-2-[[4-[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]-3-methylbutanoic acid
CFAMM00334696 CHEMBL6271 Bioactive (2R)-2-[[4-[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]-2-(3-nitrophenyl)acetic acid
CFAMM00334689 CHEMBL341334 Bioactive AC1LAB7Z

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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