CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24899
Family Name Amine oxidase [flavin-containing] B and Adenosine receptor A2b ligand N-(4-hydroxyphenyl)-4-oxochromene-3-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00472274 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor Ligand Acebutolol Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Metabotropic glutamate receptor 5 Ligand N-(3-(3-cyanobenzamid... 2 13
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-02INEQ... 6 6
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 11 26
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 1 2
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 2 5
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7496449 f... 3 2
Hepatocyte growth factor receptor ligand 2-[(2-fluorophenyl)me... 6 11
Caspase-3 inhibitor AGN-PC-00ELYM family 3 2
Neprilysin inhibitor 5-[[(2S,4S)-2-benzyl-4-carboxy-5-phenylpe... 1 0
Major prion protein and Microtubule-associated protein tau inh... 2 10
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 2 0
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 1
Urokinase-type plasminogen activator and Tissue-type plasminog... 1 0
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472275 CHEMBL1814065 Bioactive N-(3-hydroxy-4-methoxyphenyl)-4-oxochromene-3-carboxamide
CFAMM00472274 CHEMBL1814064 Bioactive N-(4-hydroxyphenyl)-4-oxochromene-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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