CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand 5-[(2-chlorophenyl)methyl]-2-[2-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]ethylsulfanyl]pyrimidine-4,6-diamine family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00309453 Functional Category Bioactive
Superfamily Aurora kinase A and Adenosine receptor A1 Binder Superfamily
Class Class 2142

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
D(4) dopamine receptor and D(2) dopamine receptor ligand N-(1-... 2 6


External ID

Functional Category

Molecule Name

CFAMM00309453 CHEMBL106176 Bioactive 5-[(2-chlorophenyl)methyl]-2-[2-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]ethylsulfanyl]pyrimidine-4,6-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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