CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24921
Family Name Low affinity sodium-glucose cotransporter and Sodium/glucose cotransporter 1 inhibitor (1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-methylsulfanylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00472378 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase and Sodium/glucose cotransporter 1 Binder Superfamily
Class Class 1347

Cousin Family NamesSeedsMembers
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Glucokinase Inhibitor R7201 Family 22 105
TS-071 family 8 36
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Sodium/glucose cotransporter 2 inhibitor (2R,3R,4S,5S,6R)-2-[4... 2 5


External ID

Functional Category

Molecule Name

CFAMM00472378 CHEMBL1819492 Bioactive (1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-methylsulfanylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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