CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24949
Family Name Hepatocyte growth factor receptor ligand 2-[(2-fluorophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide family
No. of Seeds 6 No. of Other Members 11
Family Centroid CFAMM00472480 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Niemann-Pick C1 protein Binder Superfamily 8
Class Class 4239

Cousin Family NamesSeedsMembers
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Renin Inhibitor CP-305202 Family 9 30
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Tyrosine-protein kinase ABL1 inhibitor N-(4-bromophenyl)-2-(5-... 1 3
Malate dehydrogenase, mitochondrial and Lactate dehydrogenase ... 1 1
Urokinase-type plasminogen activator and Tissue-type plasminog... 1 0
Nuclear receptor ROR-gamma and Neuropeptide S receptor ligand ... 1 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472470 CHEMBL1824371 Bioactive 2-[(3-fluorophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide
CFAMM00472469 CHEMBL1824372 Bioactive 2-[(3-chlorophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide
CFAMM00472468 CHEMBL1824373 Bioactive 2-[(3-cyanophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide
CFAMM00472481 CHEMBL1824369 Bioactive 2-[(2-cyanophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide
CFAMM00472480 CHEMBL1824368 Bioactive 2-[(2-fluorophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide
CFAMM00472471 CHEMBL1824370 Bioactive 2-[(2,6-difluorophenyl)methoxy]-N-(3-hydroxyphenyl)-4-(3-pyrrolidin-1-ylpropoxy)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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