CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2496
Family Name Vascular endothelial growth factor receptor 2 ligand AGN-PC-05IIXS family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00334826 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and Tyrosine-protein kinase JAK2 Binder Superfamily
Class Class 1542

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Neuromedin-K receptor Ligand Talnetant Family 3 49
Coagulation factor X Inhibitor Otamixaban Family 9 21
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Vascular endothelial growth factor receptor 2 ligand 5-bromo-2... 1 1
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 3 1
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Hydroxycarboxylic acid receptor 2 ligand AGN-PC-04RSPS family 4 0
Integrase inhibitor AC1LARQ6 family 1 2
ATP-dependent molecular chaperone HSP82 and Arachidonate 12-li... 1 2
Streptokinase A and Nuclear receptor ROR-gamma ligand N-[(2,4-... 4 0
Integrase inhibitor AGN-PC-00F9UX family 1 0


External ID

Functional Category

Molecule Name

CFAMM00334827 CHEMBL1271616 Bioactive AGN-PC-06HPRI
CFAMM00334826 CHEMBL1271615 Bioactive AGN-PC-05IIXS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



60878 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543