CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24961
Family Name Cruzipain and Cysteine protease inhibitor [(E)-[1-(3,4-dichlorophenyl)-3-phenylpropylidene]amino]thiourea family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00472530 Functional Category Bioactive
Superfamily Cruzipain and Cysteine protease inhibitor [(E)-[1-(3,4-dichlorophenyl)-3-phenylpropylidene]amino]thiourea Superfamily
Class Class 2727

Cousin Family NamesSeedsMembers
Cruzipain Inhibitor 3,5-dichlorobenzaldehyde Thiosemicarbazone... 2 4
Cruzipain Inhibitor 3',4'-dichloroacetophenonethiosemicarbazon... 1 6


External ID

Functional Category

Molecule Name

CFAMM00472531 CHEMBL183396 Bioactive [(E)-[(3,4-dichlorophenyl)-(2-phenylcyclopropyl)methylidene]amino]thiourea
CFAMM00472530 CHEMBL183005 Bioactive [(E)-[1-(3,4-dichlorophenyl)-3-phenylpropylidene]amino]thiourea
CFAMM00472529 CHEMBL182795 Bioactive [(E)-[(3,4-dichlorophenyl)-(4-methylphenyl)methylidene]amino]thiourea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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