Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database. Cousin Family Names Seeds Members Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76 C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52 Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101 Vascular endothelial growth factor receptor 1 and Vascular end... 4 44 Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33 Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64 Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4 Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6 Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2 Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25 Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21 Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21 Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32 5-hydroxytryptamine receptor 3A and Potassium voltage-gated ch... 1 0 Prelamin-A/C inhibitor CHEMBL1374443 family 1 6 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1 Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1 Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3 Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1 Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7 cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 27 20 Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S,... 2 3 Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8 Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0 Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,5S)-5-(... 20 10 Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 5 2 Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9 Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4 5-hydroxytryptamine receptor 6 ligand SureCN3910449 family 3 15 Somatostatin receptor type 5 ligand SureCN3572493 family 1 3
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00334852 CHEMBL1271629 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(3S)-3-propylmorpholin-4-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334865 CHEMBL1271628 Bioactive
2-[(3S)-3-ethylmorpholin-4-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334851 CHEMBL1271677 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(3S)-3-propan-2-ylmorpholin-4-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334850 CHEMBL1271730 Bioactive
2-[(3S)-3-tert-butylmorpholin-4-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334843 CHEMBL1271960 Bioactive
2-[(2S,6S)-2,6-dimethylpiperazin-1-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334849 CHEMBL1271731 Bioactive
2-[(3S,5S)-3,5-dimethylmorpholin-4-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334842 CHEMBL1271790 Bioactive
N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2-[(3S,5S)-3,5-dimethylmorpholin-4-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334841 CHEMBL1271791 Bioactive
2-[(3S,5S)-3-ethyl-5-methylmorpholin-4-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334853 CHEMBL1271678 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(3S)-3-(2-methylpropyl)morpholin-4-yl]-1,3-benzoxazole-4-carboxamide
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00334848 CHEMBL1271520 Bioactive
SureCN1005251 CFAMM00334846 CHEMBL1272122 Bioactive
SureCN1006365 CFAMM00334859 CHEMBL1272177 Bioactive
SureCN1059378 CFAMM00334845 CHEMBL1272123 Bioactive
SureCN1004351 CFAMM00334858 CHEMBL1272176 Bioactive
SureCN1007233 CFAMM00334864 CHEMBL1271571 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(3R)-3-methylmorpholin-4-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334844 CHEMBL1271959 Bioactive
2-[(2R,6R)-2,6-dimethylpiperazin-1-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334857 CHEMBL1271848 Bioactive
2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334863 CHEMBL1271519 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-morpholin-4-yl-1,3-benzoxazole-4-carboxamide CFAMM00334856 CHEMBL1271849 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-piperazin-1-yl-1,3-benzoxazole-4-carboxamide CFAMM00334862 CHEMBL2064406 Bioactive
2-[(4-methyl-1,3-benzoxazol-2-yl)methyl]-6-morpholin-4-yl-1H-pyrimidin-4-one CFAMM00334855 CHEMBL204785 Bioactive
GNF CFAMM00334861 CHEMBL1271905 Bioactive
2-[(2R,6S)-2,6-dimethylpiperazin-1-yl]-N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334854 CHEMBL1271570 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(3S)-3-methylmorpholin-4-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334847 CHEMBL1272121 Bioactive
SureCN1061799 CFAMM00334860 CHEMBL1271904 Bioactive
N-[(1R,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-[(2S)-2-methylpiperazin-1-yl]-1,3-benzoxazole-4-carboxamide CFAMM00334866 CHEMBL2064411 Bioactive
6-morpholin-4-yl-2-[(4-phenyl-1,3-benzoxazol-2-yl)methyl]-1H-pyrimidin-4-one CFAMM00334840 CHEMBL1272178 Bioactive
SureCN1005666
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Dr.
Chen Yuzong Deputy
Director of Center for Computational Science and Engineering All rights reserved.
