CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24986
Family Name Glycogen synthase kinase-3 beta inhibitor 5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-[2-(pyridin-2-ylamino)ethylamino]quinoline-3-carboxylic acid family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00472600 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta Binder Superfamily 7
Class Class 4723

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta and DNA topoisomerase 2-beta inhibito... 9 181
DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inh... 3 40
DNA topoisomerase 2-beta Inhibitor Nalidixic Acid Family 2 5
DNA topoisomerase 2-beta Inhibitor Rosoxacin Family 1 5
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Topoisomerase IV Inhibitor ABT-492 Family 1 6
Glycogen synthase kinase-3 beta inhibitor 5-amino-1-cyclopropy... 1 1
DNA polymerase III PolC-type inhibitor SureCN6783958 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472600 CHEMBL1834315 Bioactive 5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-[2-(pyridin-2-ylamino)ethylamino]quinoline-3-carboxylic acid
CFAMM00472599 CHEMBL1834318 Bioactive 5-amino-1-cyclopentyl-6,8-difluoro-4-oxo-7-[2-(pyridin-2-ylamino)ethylamino]quinoline-3-carboxylic acid
CFAMM00472605 CHEMBL1834119 Bioactive 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-(2-pyridin-4-ylethylamino)quinoline-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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