CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25001
Family Name Histone deacetylase 8 and Histone deacetylase 1 inhibitor tert-butyl N-[(2S)-1-[(8S)-8-[[6-(hydroxyamino)-6-oxohexyl]carbamoyl]-1,4-dithia-7-azaspiro[4.4]nonan-7-yl]-1-oxo-3-phenylpropan-2-yl]carbamate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00472684 Functional Category Bioactive
Superfamily Prothrombin and Pol polyprotein Binder Superfamily 3
Class Class 2530

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor Efegatran Family 9 47
Neprilysin Inhibitor Thiorphan Family 41 68
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Dipeptidyl peptidase 4 inhibitor (3S)-4-[(3R)-3-amino-4-(2,4,5... 1 1
Pol polyprotein inhibitor AC1LA4ZN family 1 1
Prothrombin inhibitor methyl (3S)-3-[[(6S,8aS)-2-benzylsulfony... 5 1
Cathepsin K inhibitor tert-butyl N-[(2R)-1-benzylsulfanyl-3-ox... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (3... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472684 CHEMBL1835416 Bioactive tert-butyl N-[(2S)-1-[(8S)-8-[[6-(hydroxyamino)-6-oxohexyl]carbamoyl]-1,4-dithia-7-azaspiro[4.4]nonan-7-yl]-1-oxo-3-phenylpropan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48713 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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