CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25006
Family Name Receptor-type tyrosine-protein kinase FLT3 ligand 1-phenyl-3-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3,5-diamine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00472707 Functional Category Bioactive
Superfamily Niemann-Pick C1 protein and Nonstructural protein 1 Binder Superfamily 3
Class Class 862

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-met... 8 0
TGF-beta receptor type-1 ligand N-(4-methoxyphenyl)-3-(6-methy... 5 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 2 2
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor AGN-... 1 0
Receptor-type tyrosine-protein kinase FLT3 ligand 4-[5-amino-3... 1 0
Serine/threonine-protein kinase PLK1 inhibitor SureCN3992071 f... 1 0


External ID

Functional Category

Molecule Name

CFAMM00472707 CHEMBL1835661 Bioactive 1-phenyl-3-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3,5-diamine
CFAMM00472705 CHEMBL1835736 Bioactive 1-(3-morpholin-4-ylphenyl)-3-N-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3,5-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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