CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25031
Family Name Cathepsin K inhibitor AGN-PC-075F1H family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00472791 Functional Category Bioactive
Superfamily DNA-(apurinic or apyrimidinic site) lyase and Cathepsin K Binder Superfamily 2
Class Class 2397

Cousin Family NamesSeedsMembers
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-(2... 1 1
Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phen... 4 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 1
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 19b family 1 1
N-formyl peptide receptor 2 ligand 2-[[(2S)-2-[(4-bromophenyl)... 2 5
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472791 CHEMBL184788 Bioactive AGN-PC-075F1H
CFAMM00472790 CHEMBL184828 Bioactive AGN-PC-075F0A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27394 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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