CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25033
Family Name Inhibitor of nuclear factor kappa-B kinase subunit beta inhibitor (6E)-2-amino-4-(2-aminoethyl)-6-(6-oxocyclohexa-2,4-dien-1-ylidene)-1H-pyridine-3-carbonitrile family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00472800 Functional Category Bioactive
Superfamily Binder Superfamily 11
Class Class 3008

Cousin Family NamesSeedsMembers
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase, cytoplasmic and Methionine--tRNA liga... 8 6
Methionine--tRNA ligase inhibitor 2-({3-[(3,5-Dichlorobenzyl)a... 5 7
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 8 3
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Steroid hormone receptor ERR1 and Steroid hormone receptor ERR... 1 4
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-amin... 4 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Estrogen receptor and Estrogen receptor beta ligand SureCN6841... 2 5
Adenosine receptor A1 ligand BAS 00727702 family 1 4
Serine/threonine-protein kinase Chk2 inhibitor (6E)-4-fluoro-6... 3 6


CFAM Mol ID

External ID

Functional Category

Molecule Name
CFAMM00472800 CHEMBL184832 Bioactive (6E)-2-amino-4-(2-aminoethyl)-6-(6-oxocyclohexa-2,4-dien-1-ylidene)-1H-pyridine-3-carbonitrile
CFAMM00472796 CHEMBL454994 Bioactive 2-amino-4-(4-oxocyclohexa-2,5-dien-1-ylidene)-6-phenyl-1H-pyridine-3-carbonitrile

Statistics of CFAM Database
 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27395 visits since 2014 .........

 


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 
Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543