CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2504
Family Name P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00334938 Functional Category Bioactive
Superfamily Farnesyltransferase beta subunit, putative and Protein farnesyltransferase subunit beta Inhibitor L-778123 Superfamily
Class Class 1486

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 9 31
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 6 3
P2X purinoceptor 7 inhibitor SureCN1635928 family 4 4
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 1 2
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1


External ID

Functional Category

Molecule Name

CFAMM00334936 CHEMBL2218149 Bioactive (4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(3-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide
CFAMM00334935 CHEMBL2218148 Bioactive (4S)-N-[(2,4-dichlorophenyl)methyl]-3-methyl-1-(3-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide
CFAMM00334934 CHEMBL2218109 Bioactive (4S)-N-[(2,4-dichlorophenyl)methyl]-3-methyl-1-(1-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide
CFAMM00334939 CHEMBL1271884 Bioactive (4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylimidazol-2-yl)-2-oxoimidazolidine-4-carboxamide
CFAMM00334938 CHEMBL1271885 Bioactive (4S)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(1-methylimidazol-4-yl)-2-oxoimidazolidine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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