CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2505
Family Name Epidermal growth factor receptor ligand 1-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6,8-dihydro-5H-pyrido[4,5]thieno[1,2-c]pyrimidin-7-yl]prop-2-en-1-one family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00334947 Functional Category Bioactive
Superfamily DNA polymerase beta and Retinal dehydrogenase 1 Binder Superfamily 2
Class Class 3569

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Vascular endothelial growth factor receptor 2 and Vascular end... 4 1


External ID

Functional Category

Molecule Name

CFAMM00334949 CHEMBL1272324 Bioactive SureCN13331198
CFAMM00334947 CHEMBL1272061 Bioactive 1-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6,8-dihydro-5H-pyrido[4,5]thieno[1,2-c]pyrimidin-7-yl]prop-2-en-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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