CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25069
Family Name Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 inhibitor aminoimidazo[1,2-a]pyridine deriv. 36 family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00472913 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 4 and Ephrin type-B receptor 3 Binder Superfamily
Class Class 256

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
IPI-145 family 2 4
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Divapl... 3 47
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 4
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 2 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 0
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Mitogen-activated protein kinase kinase kinase 5 inhibitor 4-(... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472910 CHEMBL188392 Bioactive aminoimidazo[1,2-a]pyridine deriv. 37
CFAMM00472913 CHEMBL364631 Bioactive aminoimidazo[1,2-a]pyridine deriv. 36
CFAMM00472906 CHEMBL363069 Bioactive aminoimidazo[1,2-a]pyridine deriv. 21

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27510 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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