CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25076
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor [2-(methylamino)-2-oxoethyl] (2S)-3-(1H-indol-3-yl)-2-[(4-sulfamoylphenyl)carbamothioylamino]propanoate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00472950 Functional Category Bioactive
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 17
Class Class 2185

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Endothelin B receptor Ligand IRL-2500 Family 34 87
Cathepsin L1 inhibitor Bio2_000267 family 9 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00472950 CHEMBL188774 Bioactive [2-(methylamino)-2-oxoethyl] (2S)-3-(1H-indol-3-yl)-2-[(4-sulfamoylphenyl)carbamothioylamino]propanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27669 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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