CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25109
Family Name High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A and cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor N-[4-(diethylamino)phenyl]-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00473060 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A and High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Binder Superfamily
Class Class 4695

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Neutrophil elastase inhibitor SureCN7448165 family 2 4
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 1 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 6-ter... 2 7
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 3 0


External ID

Functional Category

Molecule Name

CFAMM00473057 CHEMBL1911424 Bioactive N-(4-acetamidophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473049 CHEMBL1911418 Bioactive 1-[(2,6-difluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473062 CHEMBL1911422 Bioactive 1-[(2,6-difluorophenyl)methyl]-N-[4-(methylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473061 CHEMBL1911421 Bioactive 1-[(2,6-difluorophenyl)methyl]-N-[4-(dimethylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473060 CHEMBL1911420 Bioactive N-[4-(diethylamino)phenyl]-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473059 CHEMBL1911426 Bioactive N-(4-cyanophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
CFAMM00473058 CHEMBL1911425 Bioactive 1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-phenyl-5H-1,5-naphthyridine-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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