CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2511
Family Name Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-6-[4-[2-(benzylsulfonylamino)ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00173257 Functional Category Bioactive
Superfamily Thromboxane-A synthase Inhibitor CGS-22652 Superfamily
Class Class 1128

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Prothrombin Inhibitor Ximelegatran Family 8 157
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Coagulation factor X Inhibitor Otamixaban Family 9 21
Potassium-competitive acid Inhibitor TAK-438 Family 2 8
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
Pol polyprotein inhibitor AGN-PC-0AAPKK family 2 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand 3-[(... 3 0
Pol polyprotein inhibitor AGN-PC-0AAOIM family 4 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand (E)-... 2 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 3 0
Pol polyprotein inhibitor Lysine Sulfonamide 6h family 1 1
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S,4R)... 2 2
Thromboxane-A synthase inhibitor 7-[(2S,3R)-3-pyridin-3-yl-2-b... 1 1
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 1 0
Thromboxane-A synthase inhibitor (Z)-2-bromo-3-[4-(pyridin-3-y... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 0
Thromboxane-A synthase inhibitor SureCN9825871 family 6 3
Cytochrome P450 2C19 inhibitor AGN-PC-07CPMJ family 1 0
Peptidyl-prolyl cis-trans isomerase FKBP1A and Outer membrane ... 2 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-[[2-[3... 4 0
heptanamide NP ZINC08740384 Family 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334993 CHEMBL415519 Bioactive (E)-6-[4-[2-(butylsulfonylamino)ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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