CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25137
Family Name fMet-Leu-Phe receptor ligand N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-fluorophenyl)-3-methyl-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]pyrazole-4-carboxamide family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00473140 Functional Category Bioactive
Superfamily fMet-Leu-Phe receptor and Survival motor neuron protein Binder Superfamily
Class Class 4482

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
fMet-Leu-Phe receptor ligand N-[(2S)-3,3-dimethylbutan-2-yl]-1... 1 13
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5


External ID

Functional Category

Molecule Name

CFAMM00473137 CHEMBL1916284 Bioactive N-[(2S)-3,3-dimethylbutan-2-yl]-5-[(4-methylphenyl)sulfonylamino]-1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxamide
CFAMM00473141 CHEMBL1916288 Bioactive 5-[(4-cyanophenyl)sulfonylamino]-N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-fluorophenyl)-3-methylpyrazole-4-carboxamide
CFAMM00473140 CHEMBL1916289 Bioactive N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-fluorophenyl)-3-methyl-5-[[4-(trifluoromethyl)phenyl]sulfonylamino]pyrazole-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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