CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25142
Family Name Caspase-3 inhibitor 2-[8-morpholin-4-ylsulfonyl-1,3-dioxo-4-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]pyrrolo[3,4-c]quinolin-2-yl]ethyl acetate family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00473168 Functional Category Bioactive
Superfamily Caspase-3 and Niemann-Pick C1 protein Binder Superfamily
Class Class 3980

Cousin Family NamesSeedsMembers
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 4 21
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Caspase-3 inhibitor pyrrolo[3,4-c]quinoline 8f family 1 16


External ID

Functional Category

Molecule Name

CFAMM00473167 CHEMBL426991 Bioactive AGN-PC-009OWI
CFAMM00473168 CHEMBL191738 Bioactive 2-[8-morpholin-4-ylsulfonyl-1,3-dioxo-4-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]pyrrolo[3,4-c]quinolin-2-yl]ethyl acetate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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