CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25150
Family Name Transient receptor potential cation channel subfamily V member 1 ligand SureCN13675700 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00473187 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 Binder Superfamily 9
Class Class 5006

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
DNA Binder Primaquine Family 3 245
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Sigma non-opioid intracellular receptor 1 and Kappa-type opioi... 3 12
Transient receptor potential cation channel subfamily V member... 2 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 3 0
P2Y purinoceptor 1 inhibitor 1-(4-tert-butylphenyl)-3-[2-(2-pr... 4 14
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Transient receptor potential cation channel subfamily V member... 6 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Rho-associated protein kinase 2 and RAC-alpha serine/threonine... 1 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 0
Transient receptor potential cation channel subfamily V member... 2 0
Menin and Histone-lysine N-methyltransferase 2A inhibitor CHEM... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473187 CHEMBL191768 Bioactive SureCN13675700
CFAMM00473190 CHEMBL194449 Bioactive SureCN13675699
CFAMM00473189 CHEMBL485213 Bioactive pyridine-phenyl, 2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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