CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25177
Family Name NADPH oxidase 4 and NADPH oxidase 1 inhibitor 2-(2-chlorophenyl)-10-(pyridin-3-ylmethyl)-7,8,9,11-tetrahydro-3H-pyrazolo[4,5]pyrido[5,6-a][1,4]diazepine-1,5-dione;hydrochloride family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00473289 Functional Category Bioactive
Superfamily NADPH oxidase 4 and NADPH oxidase 1 Binder Superfamily 2
Class Class 1532

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase Inhibitor Ici 207968 Family 3 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Prothrombin inhibitor SureCN7371121 family 13 3
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 8 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 6 4
NADPH oxidase 4 inhibitor 4-[[benzyl(methyl)amino]methyl]-2-(2... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473289 CHEMBL1927156 Bioactive 2-(2-chlorophenyl)-10-(pyridin-3-ylmethyl)-7,8,9,11-tetrahydro-3H-pyrazolo[4,5]pyrido[5,6-a][1,4]diazepine-1,5-dione;hydrochloride
CFAMM00473288 CHEMBL1927157 Bioactive 2-(2-chlorophenyl)-10-(pyridin-2-ylmethyl)-7,8,9,11-tetrahydro-3H-pyrazolo[4,5]pyrido[5,6-a][1,4]diazepine-1,5-dione;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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