CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25190
Family Name Dihydroorotate dehydrogenase (quinone), mitochondrial inhibitor methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-phenylbenzoate family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00473342 Functional Category Bioactive
Superfamily Dihydroorotate dehydrogenase (quinone), mitochondrial and Beta-lactamase Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 0


External ID

Functional Category

Molecule Name

CFAMM00473344 CHEMBL1929436 Bioactive methyl 2-(2-chlorophenyl)-5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]benzoate
CFAMM00473342 CHEMBL1929434 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-phenylbenzoate
CFAMM00473341 CHEMBL1929438 Bioactive methyl 2-(4-chlorophenyl)-5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]benzoate
CFAMM00473347 CHEMBL1929443 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(4-fluoro-2-methylphenyl)benzoate
CFAMM00473340 CHEMBL1929441 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(2,4-difluorophenyl)benzoate
CFAMM00473346 CHEMBL1929445 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(3,4-difluorophenyl)benzoate
CFAMM00473345 CHEMBL1929437 Bioactive methyl 2-(3-chlorophenyl)-5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55505 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543