CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25191
Family Name Dihydroorotate dehydrogenase (quinone), mitochondrial inhibitor methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(4-fluoro-2-methoxyphenyl)benzoate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00473349 Functional Category Bioactive
Superfamily Dihydroorotate dehydrogenase (quinone), mitochondrial and Beta-lactamase Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 8 39
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Transient receptor potential cation channel subfamily V member... 1 2
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1
Capsid scaffolding protein inhibitor AC1MHP20 family 3 3
Leukotriene B4 receptor 1 ligand 4-methoxy-3-[[(E)-3-(4-phenyl... 2 10
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 7 6
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 1
3,5-bis[[2-(4-methoxyphenoxy)acetyl]amino]benzoate NP Agn-pc-0... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473349 CHEMBL1929447 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(4-fluoro-2-methoxyphenyl)benzoate
CFAMM00473348 CHEMBL1929453 Bioactive methyl 5-[[(Z)-2-cyano-3-hydroxypent-2-enoyl]amino]-2-(3-cyclobutyloxyphenyl)benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27261 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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