CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25209
Family Name Beta-secretase 1 inhibitor [(3'S,4R)-7-bromospiro[2,3-dihydro-1H-naphthalene-4,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00473428 Functional Category Bioactive
Superfamily Prothrombin and Beta-secretase 1 Binder Superfamily
Class Class 3621

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(3-... 1 7
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 5 1
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Cannabinoid receptor 2 ligand 1-adamantyl(1,3-dihydroisoindol-... 1 0
Prothrombin inhibitor 1-(2-amino-3,3-diphenylpropanoyl)-N-[(3-... 1 1


External ID

Functional Category

Molecule Name

CFAMM00473428 CHEMBL1934293 Bioactive [(3'S,4R)-7-bromospiro[2,3-dihydro-1H-naphthalene-4,4'-pyrrolidine]-3'-yl]-[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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