CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25221
Family Name DNA polymerase III PolC-type inhibitor HB-EMAU family
No. of Seeds 17 No. of Other Members 7
Family Centroid CFAMM00473517 Functional Category Bioactive
Superfamily DNA polymerase III PolC-type and Lethal factor Binder Superfamily
Class Class 2986

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Androgen receptor Ligand YM-175735 Family 30 129
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
DNA topoisomerase Inhibitor 6-(indan-5-ylamino)-1h-pyrimidine-... 2 0
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
DNA polymerase III PolC-type inhibitor SureCN3470957 family 7 0
DNA polymerase III PolC-type inhibitor SureCN3473660 family 2 0
DNA polymerase III PolC-type inhibitor SureCN3471150 family 1 0
DNA polymerase III PolC-type inhibitor [5-[[3-(4-methoxybutyl)... 2 2
DNA polymerase III PolC-type inhibitor 6-(3-chloro-4-methylani... 1 1
DNA polymerase III PolC-type inhibitor 3-(4-hydroxybutyl)-6-(3... 1 0


External ID

Functional Category

Molecule Name

CFAMM00473506 CHEMBL199022 Bioactive SureCN3471758
CFAMM00473519 CHEMBL196000 Bioactive SureCN7039037
CFAMM00473499 CHEMBL194208 Bioactive SureCN3471090
CFAMM00473518 CHEMBL196895 Bioactive SureCN3471990
CFAMM00473498 CHEMBL197670 Bioactive SureCN3471507
CFAMM00473511 CHEMBL198437 Bioactive 6-(3-ethyl-4-methylanilino)-3-(10-hydroxydecyl)-1H-pyrimidine-2,4-dione
CFAMM00473504 CHEMBL193796 Bioactive SureCN3470402
CFAMM00473517 CHEMBL327687 Bioactive HB-EMAU
CFAMM00473497 CHEMBL427358 Bioactive 6-(3-ethyl-4-methylanilino)-3-(9-hydroxynonyl)-1H-pyrimidine-2,4-dione
CFAMM00473510 CHEMBL198822 Bioactive SureCN3470792
CFAMM00473516 CHEMBL194748 Bioactive 6-(3-ethyl-4-methylanilino)-3-[4-(2-hydroxyethylamino)butyl]-1H-pyrimidine-2,4-dione
CFAMM00473496 CHEMBL370565 Bioactive SureCN3471995
CFAMM00473509 CHEMBL197697 Bioactive SureCN3477110
CFAMM00473502 CHEMBL373043 Bioactive SureCN7040415
CFAMM00473515 CHEMBL196406 Bioactive 5-[6-(3-ethyl-4-methylanilino)-2,4-dioxo-1H-pyrimidin-3-yl]pentyl acetate
CFAMM00473514 CHEMBL196264 Bioactive 3-[4-[bis(2-hydroxyethyl)amino]butyl]-6-(3-ethyl-4-methylanilino)-1H-pyrimidine-2,4-dione
CFAMM00473507 CHEMBL371354 Bioactive SureCN3470805

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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