CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25222
Family Name DNA polymerase III PolC-type inhibitor SureCN3470957 family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00473526 Functional Category Bioactive
Superfamily DNA polymerase III PolC-type and Lethal factor Binder Superfamily
Class Class 2986

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
DNA topoisomerase Inhibitor 6-(indan-5-ylamino)-1h-pyrimidine-... 2 0
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 3 2
DNA polymerase III PolC-type inhibitor HB-EMAU family 17 7
DNA polymerase III PolC-type inhibitor SureCN3473660 family 2 0
DNA polymerase III PolC-type inhibitor SureCN3471150 family 1 0
DNA polymerase III PolC-type inhibitor [5-[[3-(4-methoxybutyl)... 2 2
DNA polymerase III PolC-type inhibitor 6-(3-chloro-4-methylani... 1 1
DNA polymerase III PolC-type inhibitor 3-(4-hydroxybutyl)-6-(3... 1 0


External ID

Functional Category

Molecule Name

CFAMM00473524 CHEMBL193797 Bioactive 6-(3-ethyl-4-methylanilino)-3-(8-morpholin-4-yloctyl)-1H-pyrimidine-2,4-dione
CFAMM00473523 CHEMBL90265 Bioactive SureCN3470220
CFAMM00473522 CHEMBL93921 Bioactive 3-[4-(2-ethoxymorpholin-4-yl)butyl]-6-(3-ethyl-4-methylanilino)-1H-pyrimidine-2,4-dione
CFAMM00473521 CHEMBL89968 Bioactive ethyl 2-[4-[4-[6-(3-ethyl-4-methylanilino)-2,4-dioxo-1H-pyrimidin-3-yl]butyl]morpholin-2-yl]acetate
CFAMM00473520 CHEMBL197002 Bioactive SureCN3470641
CFAMM00473526 CHEMBL557634 Bioactive SureCN3470957
CFAMM00473525 CHEMBL439683 Bioactive SureCN3470828

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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