CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25247
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 4-[(6-chloro-3,8-dimethyl-2H-pyrazolo[3,4-b]quinolin-4-yl)methyl]-1,4-oxazepane family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00473606 Functional Category Bioactive
Superfamily cAMP and Corticotropin-releasing factor receptor 1 Binder Superfamily
Class Class 37

Cousin Family NamesSeedsMembers
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Ribosomal protein S6 kinase beta-1 and RAC-alpha serine/threon... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
Serine/threonine-protein kinase Chk1 inhibitor N'-(8-chloro-3-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473608 CHEMBL1940067 Bioactive 5-[(6-chloro-3,8-dimethyl-2H-pyrazolo[3,4-b]quinolin-4-yl)methyl]-2-oxa-5-azabicyclo[2.2.1]heptane
CFAMM00473606 CHEMBL1940061 Bioactive 4-[(6-chloro-3,8-dimethyl-2H-pyrazolo[3,4-b]quinolin-4-yl)methyl]-1,4-oxazepane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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