CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25258
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand N-benzyl-7-(dimethylamino)-4-oxo-1H-1,8-naphthyridine-3-carboxamide family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00466701 Functional Category Bioactive with Natural Product
Superfamily Adenosine receptor A2a and Adenosine receptor A1 Binder Superfamily 4
Class Class 2020

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Reverse transcriptase/RNaseH inhibitor Dipyridodiazepinone der... 1 8
Ephrin type-A receptor 3 and Tyrosine-protein kinase Fgr ligan... 1 3
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 4


External ID

Functional Category

Molecule Name

CFAMM00473648 CHEMBL194696 Bioactive 7-methyl-N-[(4-nitrophenyl)methyl]-4-oxo-1H-1,8-naphthyridine-3-carboxamide
CFAMM00473651 CHEMBL194539 Bioactive N-benzyl-7-chloro-4-oxo-1H-1,8-naphthyridine-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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