CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2526
Family Name Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpyridin-4-yl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00335095 Functional Category Bioactive with Natural Product
Superfamily Chymase and Liver carboxylesterase 1 Binder Superfamily
Class Class 963

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Cannabinoid receptor 1 Ligand Taranabant Family 20 30
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Chymase Inhibitor NK3201 Family 1 0
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Beta-secretase 1 and Cathepsin D inhibitor N-[(2S,3R)-4-[[(4S)... 34 23
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 3 1
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Renin inhibitor SureCN7300793 family 2 5
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-met... 1 1
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335100 CHEMBL509480 Bioactive (1R,5S)-3-acetyl-N-cyclopropyl-N-[(3-methoxy-2-methylpyridin-4-yl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00335095 CHEMBL1276274 Bioactive (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpyridin-4-yl)methyl]-7-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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