CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25261
Family Name Nitric oxide synthase, inducible inhibitor N-(3-chlorophenyl)-N-[(7,8-difluoro-2-oxidoisoquinolin-2-ium-4-yl)methyl]pyrimidin-2-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00473664 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 and Sodium channel protein type 1 subunit alpha Binder Superfamily
Class Class 2568

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Metabotropic glutamate receptor 5 Ligand 2-(3,5-dichlorophenyl... 2 3
Metabotropic glutamate receptor 5 Ligand 5-(2-(3-chlorophenyl)... 2 13
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Tyrosine-protein kinase ABL1 and Mitogen-activated protein kin... 1 3
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 0
Dihydrofolate reductase inhibitor 6-[[(4-chloronaphthalen-1-yl... 2 1
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 3
Vascular endothelial growth factor receptor 2 and Fibroblast g... 5 2
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 3 4
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 14 14
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473664 CHEMBL1945068 Bioactive N-(3-chlorophenyl)-N-[(7,8-difluoro-2-oxidoisoquinolin-2-ium-4-yl)methyl]pyrimidin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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